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ET said well if A leads to B ) Tj EMC BT stream ET EMC 0000178962 00000 n 134 0 obj<> /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw endstream ET But there is a lot about how sugar operates that we may not have realized before. 0000002246 00000 n ET ET EMC EMC endstream endstream stream BT ET stream (down to AMP adenosine monophosphate down to IMP Inositol monophosphate and finally to the ) Tj endobj endstream (with glucose. /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw EMC stream stream Are aldehydes ) Tj 0000076685 00000 n endstream Tj 0000083242 00000 n 0000058164 00000 n we are. 0000036591 00000 n endstream And we have to figure out what caused it and how to reverse it, and thats what tonight is about. Wow? endstream ET stream 0000105750 00000 n endstream No, we didn't. stream endobj ET Now in order to talk about the environment we need to talk about what is obesity, and of course, youre all familiar with the basic concept of the first law of thermodynamics, which states that the total energy inside a closed system remains constant. EMC ET 442 0 obj<> 529 0 obj<> (the same time to create this perfect storm. endobj 463 0 obj<> 72.000000 468.000000 Td 0000114204 00000 n stream stream 685 0 obj<> ET endstream A little extra sugar may seem harmless, but ingested often, it can contribute to a variety of health issues, like obesity, diabetes, and heart disease. /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw endobj BT /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw 72.000000 95.000000 Td endobj (mitochondria. 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BT endstream ET 0000023569 00000 n BT endstream ET /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw (is good.) (showed in our clinic. endobj 495 0 obj<> 72.000000 597.000000 Td 851 0 obj<> EMC endstream EMC endobj 72.000000 486.000000 Td ET Now where do these inner-city Harlem toddlers get their ) Tj 72.000000 537.000000 Td 72.000000 497.000000 Td By the end of the story, I hope I will have debunked the last 30 years of nutrition information in America. (No question about it. stream (because they are the same, they come from the same place. The question is who is ) Tj 79 0 obj<> (sucrose too, because these guys here eat doughnuts. /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw ET Everybody knows what that is now. 0000119412 00000 n EMC And as far as I'm concerned, it has a hole as big as the one in the USS Cole. ) 33 0 obj<> BT So four times the substrate is going to hit the liver and ) Tj Question is why? stream ET EMC /FNT_Courier_Bold 9.090909 Tf 95.000000 Tz 0.000000 Tw /FNT_Courier_Bold 9.090909 Tf 95.000000 Tz 0.000000 Tw EMC (front page of Time Magazine in 1980. It has nothing to do with the calories. 72.000000 709.000000 Td BT 522 0 obj<> 72.000000 251.000000 Td 0000065206 00000 n 72.000000 219.000000 Td 229 0 obj<> (you look at your triglyceride level in association with it. EMC EMC endstream EMC endobj BT endobj 0000041014 00000 n ET 696 0 obj<> EMC So when you actually compute the number of calories ) Tj 72.000000 307.000000 Td And you will tell me if I was successful.) Anybody remember this bottle? 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ET endobj stream 0000050309 00000 n EMC 784 0 obj<> stream 72.000000 253.000000 Td 512 0 obj<> endstream ET endobj ET /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw EMC BT EMC 0000070109 00000 n endstream 0000103188 00000 n 680 0 obj<> EMC 705 0 obj<> (Obesity research shows high fructose corn syrup metabolizes and impacts satiety similar ) Tj BT endstream Now let me show you why.) BT /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw (same reason through the same mechanism and the same dosing is also a toxin. ) But indeed this is true. Now this was done before computers. stream stream stream ET endstream BT endobj stream endobj BT EMC (We follow our patients every three months. 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And that is, if you're going to store it, ) Tj endstream BT /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw BT ET /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw ET endstream endstream EMC And so most fructose items when you put it together, now we are up ) Tj 72.000000 654.000000 Td endobj endobj /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw endstream ET stream ET 72.000000 240.000000 Td stream ET 72.000000 218.000000 Td (pressure low. 72.000000 140.000000 Td endstream Dr. Robert Lustig: "Fat Chance: Beating The Odds Against Sugar ET EMC Almost everything. endstream 318 0 obj<> 0000005003 00000 n endstream 473 0 obj<> /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw endobj BT (per day. 72.000000 720.000000 Td stream EMC ET (never heard about much before. 72.000000 319.000000 Td 72.000000 597.000000 Td endstream endobj So that little Japanese guy with a little hat,) Tj endstream stream endstream endstream /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw endobj ET 0000050552 00000 n 768 0 obj<> endstream /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw It tasted like something ) Tj (1970s, we discovered something in our blood called LDL, low density lipoproteins. stream (sucrose, the xylulose 5-phosphate goes way up with the sucrose. ET /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw endstream stream /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw EMC If you're going to store it and you expect to burn it, then youre going to ) Tj stream BT You got to be joking me. (which I'll show you when we talk about fructose. ) /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw endstream stream EMC 72.000000 519.000000 Td EMC BT ET stream stream (regression analysis the thing that made it not work. Tj ET EMC 297 0 obj<> BT Because its all ) Tj stream BT BT (1967, University of Florida patents Gatorade. endobj (consumption and obesity. EMC If you haven't studied biochemistry, ) Tj BT endstream 72.000000 329.000000 Td (muscle and brain will consume the other 10%. 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BT endobj ET endobj stream endstream /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw 0000141162 00000 n endstream 72.000000 598.000000 Td EMC So tonight were going to talk about the environment rather than genes. /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw I don't anymore. endobj endobj endobj endobj /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw endstream /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw endobj 872 0 obj<> (question to you - granted this is a physiology question - is how much glycogen can your ) Tj stream ET endstream Thats what exercise does, ) Tj /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw stream endobj ET BT BT That's the point. 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Now in human terms, the standard interpretation of this law is the following: If you eat it, you better burn it or you can store it. endstream BT ET endstream ET (the mitochondria through a process known as the citrate shuttle and then that citrate can ) Tj ET EMC /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw BT endobj 72.000000 497.000000 Td stream Thats exactly the point. ) 322 0 obj<> stream EMC 72.000000 441.000000 Td 72.000000 296.000000 Td EMC 604 0 obj<> 0000088871 00000 n ET 0000128592 00000 n endstream (So how about type 2 diabetes? endobj ET 72.000000 575.000000 Td /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw 0000105088 00000 n BT BT stream /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw (that fructose does that glucose doesn't. endstream (and actually causes what we call developmental programming changing the kids adiposity ) Tj stream ET stream stream stream endobj ET 479 0 obj<> BT stream EMC Didnt I tell you the Japanese ) Tj 72.000000 244.000000 Td /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw endstream endstream I dare you other than a salad, I dare you to ) Tj /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw EMC Now ) Tj endstream /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw stream They are bad. endstream Sugar - The bitter truth on Vimeo BT But as the of circuit court ) Tj 72.000000 675.000000 Td So when people talk about high-fat diets doing bad ) Tj endobj BT EMC EMC stream endstream 553 0 obj<> ET stream EMC BT BT ET /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw And I would very much appreciate if at the end of the talk you would tell me whether or not I was successful or not. endobj (they float. 0000061006 00000 n 0000183461 00000 n 0000168794 00000 n EMC endobj EMC 72.000000 250.000000 Td (it. ET BT BT Tj stream 895 0 obj<> BT endstream /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw stream BT stream endobj 96 calories of the 120 calories are going to the liver. If you stress reduce what do ) Tj 72.000000 104.000000 Td endobj (buy. 882 0 obj<> endstream ET endstream endobj 72.000000 665.000000 Td endstream endstream I dont ) Tj endstream 572 0 obj<> 72.000000 375.000000 Td 72.000000 331.000000 Td 72.000000 519.000000 Td stream 0000003896 00000 n 0000101093 00000 n ET endobj (And here is sucrose. /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw BT 693 0 obj<> (everyday and then of course over here we have the 7-Eleven Big K, Thirst Buster, Big Gulp ) Tj (membered ring. 72.000000 424.000000 Td ET /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw stream endstream ET (getting that 100 to 300 grams of fiber I mentioned before. endstream endobj endobj 674 0 obj<> 192 0 obj<> BT EMC ET /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw 72.000000 642.000000 Td ( gluttony and slough are actually secondary to a biochemical process, which is primary. ) EMC EMC BT EMC endobj 72.000000 720.000000 Td ET 0000189693 00000 n So we decided to do a full transcript on his about 90-minute YouTube video called Sugar: The Bitter Truth. EMC BT stream BT EMC /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw 0000011252 00000 n (drinks? stream They did. /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw 72.000000 465.000000 Td BT /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw ET 0000213739 00000 n BT stream BT 352 0 obj<> EMC (minute. endstream BT Tj stream 0000065915 00000 n So where are they? (are eating 187 calories more per day. 0000112296 00000 n endobj 669 0 obj<> endobj stream EMC endobj stream stream BT stream endobj EMC After all you see anybody on the street, hes a glutton and slough. endstream Tj BT 72.000000 374.000000 Td /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw BT ET ET You have the answer right there. ) If you did that everyday for a year, ) Tj 0000055509 00000 n 14 0 obj<> Fat kids drink it. (Ethanol is also a carbohydrate) Tj EMC Okay so before we go on, Ill just want to now digress for a moment.) 0000191336 00000 n BT stream Tj 0000181308 00000 n 72.000000 284.000000 Td BT endstream Tj ET EMC 72.000000 330.000000 Td /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw 0000199111 00000 n ET endstream 72.000000 230.000000 Td endstream stream /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw BT Teen boys are eating 275 calories more. EMC 0000218264 00000 n /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw BT (Obesity epidemic) Tj 0.000000 0.000000 0.000000 rg endobj BT 130 0 obj<> Originally Uploaded by 'University of California Television' (UCTV) in July 30th, 2009. ET (glucose? No question. /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw 448 0 obj<> If you all want to see ) Tj stream 0000125461 00000 n ET I am done and I can burn energy ) Tj endstream 411 0 obj<> 0000072952 00000 n 72.000000 308.000000 Td 0000003236 00000 n EMC /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw 72.000000 362.000000 Td 72.000000 106.000000 Td EMC endobj ET 484 0 obj<> 0000023083 00000 n EMC Not so bad. stream (composer, he retired at age 37 to a lifetime of gastronomic debauchery. (Some of the acetyl-CoA wont even make it out and will precipitate as a lipid droplet. endstream BT endstream BT BT EMC BT endobj BT (to bind to its receptor and its going to take this substrate over here called IRS-1 ) Tj ET endobj endobj 0000153409 00000 n endstream stream 0000053348 00000 n (Conclusion) Tj /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw 72.000000 264.000000 Td So there ) Tj Tj ET /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw EMC 0000185856 00000 n (That's exactly right. Sure. 0000051034 00000 n 447 0 obj<> /FNT_Courier 9.090909 Tf 95.000000 Tz 0.000000 Tw 0000202261 00000 n (the body can use glucose. 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