(Hemoglobin is a protein thats found in red blood cells.). He said sometimes the reaction does show up after a few doses and unfortunately it takes longer to get over it. If you have diarrhea while youre taking Injectafer, call your doctor. What to know about iron deficiency anemia, took oral iron treatment and didnt have improvement in their IDA or had side effects that couldnt be managed, or, swelling under your skin, typically in your eyelids, lips, hands, or feet, swelling of your tongue, mouth, or throat, have a medical condition that affects their bodys ability to absorb phosphorus, take medications that affect how well their, ferrous sulfate (Fer-Iron, Slow-FE, Feosol), people who took Injectafer had their hemoglobin level increase by an average of 1.1 grams per deciliter (g/dL), people who took Venofer had their hemoglobin increase by an average of 0.9 g/dL. You may report side effects to the FDA at 1-800-332-1088. Constipation,dry mouth, headaches, upset stomach, and many othercommonside effectscan greatly affect peoples quality of life, though. It is given into a vein for a period of time. Brand-name medications usually cost more than generics. (A generic drug is an exact copy of the active drug in a brand-name medication.) Venofer Side Effects. Renal elimination is negligible. In pediatric patients the most common side effects (>2%) are headache, viral respiratory tract infection, peritonitis, upset stomach, throwing up, fever, dizziness, cough, arteriovenous fistula thrombosis, hypotension and hypertension (increased blood pressure). Injectafer and Feraheme are both brand-name drugs. Venofer (iron sucrose) can also be mixed in a saline solution and given through an IV over a longer time. Maximum concentrations of Injectafer are achieved within 15 minutes to 1.21 hours following administration. Source: Wolters Kluwer Health. Iron sucrose can also be mixed in a saline solution and given through an IV over a longer time. But its not known whether this poses any risk to a child whos breastfed. Injectafer and Feraheme have different approved uses, but theyre both used to treat IDA in certain adults. monitor along with your hemoglobin and red blood cell count: The Venofer patient brochure provides information and support for CKD patients (2 years and older) with IDA. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. If you have symptoms of a low phosphorus level, call your doctor. This means that your doctor and insurance company will need to communicate about your prescription before the insurance company will cover the drug. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. In fact, Injectafer is meant for some people whose anemia didnt improve with iron pills or for people who had side effects from iron pills. Serious side effects should be reported to a physician and/or PharmD for medical advice. If either is present, do not use the liquid. Venofer may cause significant hypotension (decreased blood pressure). Mild side effects of Injectafer can include:*. To learn about other mild side effects, talk with your doctor or pharmacist, or see Injectafers package insert. If your symptoms or health problems do not get better or if they become worse, call your doctor. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. If youre taking iron pills, be sure to tell your doctor before starting Injectafer. Their medical staff can help you set up another time to receive your Injectafer dose. Symptoms of overdosage include drowsiness, mental confusion, dizziness, diarrhea and vomiting etc. Medically reviewed by Sanjai Sinha, MD. Notify your healthcare provider if you are pregnant, or planning to get pregnant or breastfeeding. And this person had gotten their first dose of the drug without having an allergic reaction. Call your doctor right away if you have chest pain, cough or the need to cough, dizziness, passing out, shortness of breath, sweating, or throat tightness. fruit-like breath odor increased hunger or thirst increased urination lack or loss of strength pain or redness at the injection site pale skin at the injection site runny nose, sneezing sore throat unexplained weight loss Rare Burning, dry, or itching eyes discharge or excessive tearing Weight changes may be due to symptoms of anemia improving. After getting each dose of Injectafer, your healthcare professional will monitor you for at least 30 minutes. Theyll recommend how to manage your condition. There are currently no generic forms of either drug. Why is the range so wide? stream Injectafer and Feraheme can cause very similar side effects, but some different ones as well. It can also cause skin irritation and redness. And theyll recommend how soon after starting the drug you need to have this level checked. This medicine is sometimes given slowly, and the infusion can take up to 2.5 hours to complete. Blood tests may be needed to check for unwanted effects. For example, if someone takes 100 mg of a drug, only half of it will be in the bloodstream in a couple ofhours. Laboratory tests (such as complete blood count, ferritin, transferrin, total iron binding capacity-TIBC) should be performed periodically to monitor your progress or check for side effects. Muscle cramps, nausea, vomiting, strange taste in the mouth, diarrhea, constipation, headache, cough, back pain, joint pain, dizziness, or swelling of the arms/legs may occur. In order for your body to make RBCs, your bone marrow needs a hormone called erythropoietin (EPO). With anemia, you have a low level of red blood cells (RBCs) in your body. Injectafer is approved to treat iron deficiency anemia (IDA). The Food and Drug Administration (FDA) approves prescription drugs such as Injectafer to treat certain conditions. Fortunately, knowing how longside effectslast can help those suffering know what to donext. If you come into contact with Red Tide, it can cause respiratory irritation, coughing, and sneezing. In some cases, they may even recommend that you use a drug other than Injectafer to treat your anemia. FG Trade/E+ sia Getty Images These lists contain examples of serious side effects that can occur with Injectafer, with Feraheme, or with both drugs (when taken individually). Do not flush down a toilet or pour down a drain unless you are told to do so. Signs of high or low blood pressure like very bad headache or dizziness, passing out, or change in eyesight. Iron sucrose can also be mixed in a. Tell your caregivers right away if you have: problems with your dialysis vein access point; high blood pressure - severe headache, blurred vision, pounding in your neck or ears; low blood pressure - a light-headed feeling, like you might pass out; or. Orofer S 100 Injection 1 Injection in 1 Packet 286 301 5% off. Venofer is manufactured under license from Vifor (International) Inc., Switzerland. One of the most commonly used tests to monitor IDA is the hemoglobin test. After 5 weeks of treatment: This study didnt determine if either drug was better than the other. Pain in your limbs. Injectafer is indicated to treat iron deficiency anemia (IDA) in adults who meet one of the following criteria: Injectafer is administered intravenously, either by intravenous (IV) infusion or as an undiluted, slow IV push. weakness. Serious side effects from Injectafer arent common, but they can occur. Venofer is for use in adults and children at least 2 years old. Follow your doctor's directions carefully. Should I avoid certain foods while taking Venofer Vial? *Patients are calculated based on an estimated annual cumulative dose. Venofer can be given as a maximum of 200mg not more than 3 times per week; doses must be 24 hours apart. 4 0 obj Do not share your drugs with others and do not take anyone else's drugs. For instance, those who are taking other medications or supplements as part of home remedies may continue to suffer from the ill effects of their new medication because they dontinteract. administered at your doctors office or an infusion center. Nausea. Drug interactions: DayQuil can interact with other medications, including prescription drugs, over-the-counter medications, and herbal supplements. Iron is an essential nutrient needed to maintain energy levels and keep you healthy. These changes could help improve your anemia on a long-term basis. (A medication class is a group of medications that work in a similar way.). Both Injectafer and Feraheme belong to a class of medications known as iron replacement products. How long it takes for the bodyto break down the meds matters and some peoples bodies simply take longer than others. So the goal of anemia treatment is to increase your hemoglobin level back to a value thats within a normal range. In clinical trials, pregnant females* who took Injectafer didnt have any negative outcomes, such as premature delivery or pregnancy loss. It depends. Additional studies are ongoing to see if Injectafer is a safe and effective treatment option for these conditions. Generics tend to cost less than brand-name drugs. A very serious allergic reaction to this drug is unlikely, but get medical help right away if it occurs. After receiving IV iron therapy, you will be monitored for 30 minutes to make sure you do not have an allergic reaction or a drop in blood pressure. If you are using this medication at home, learn all preparation and usage instructions from your health care professional. Injectafer contains the active drug ferric carboxymaltose. endobj The oral form of the drug, called sucroferric oxyhydroxide and used . For example: Say you weigh 105 pounds (about 48 kilograms). You should not be treated with this medicine if you have ever had an allergic reaction to an iron injection. You should not receive Venofer if you have known allergies to iron sucrose. Iron sucrose can make it harder for your body to absorb iron medications you take by mouth. Answer by DrLact: About Venofer usage in lactation. %PDF-1.3 Severeside effectsmay end up causing a lot of disruption in a persons life. These symptoms can include: While youre taking Injectafer, your doctor will monitor your phosphorus levels if youre at risk for hypophosphatemia. We cancelled my 5th because of the reaction. As described just above in the Allergic reaction section, some people may have an allergic reaction after getting a dose of Injectafer. People who weigh 110 pounds (about 50 kilograms) or more will receive two separate Injectafer doses of 750 milligrams each. As with all medications, the cost of Injectafer can vary. Venofer pregnancy and breastfeeding warnings. These include: Note: For more information about the potential negative effects of Injectafer, see the Injectafer side effects section above. Erectile dysfunction, anothercommonside effect, can affect life significantly leading to depression and failedrelationships. Theyll likely have you stop taking the pills while youre using Injectafer. Weight Loss for Health and Longevity, Science Reveals How Red Meat Harms the Heart, Flavored Vapes Still in Stores Despite Federal Ban, New COVID Antiviral Pills: What You Need to Know, Dr. Whyte's Book: Take Control of Your Cancer Risk, WebMD Loses Cherished Leader Kristy Hammam, Health News and Information, Delivered to Your Inbox, Treating Opioid Use Disorder With Medications, Constipated? WebMD does not provide medical advice, diagnosis or treatment. Injectafer isnt available in a generic form. The benefit of treating your condition during pregnancy may outweigh any risks. A shortage of iron can cause health problems. 2022 American Regent, Inc.PP-VE-US-0016 (v6.0)1/2022, Iron is also necessary for your bone marrow to build healthy new red blood cells and provide oxygen to your organs and tissues through hemoglobin, If you or your child has been prescribed Venofer, its based on your blood work, which shows how many red blood cells you have and whether you have enough iron in your blood cells, If you are iron deficient, raising your iron levels can help increase your hemoglobin levels, Treating your anemia may help prevent future health problems, Over time, untreated IDA can cause heart problems; if you already have heart problems, it can make those problems worse, Venofer is given intravenously (through an IV) and Talk with your doctor. If you miss a dose, ask your doctor or pharmacist right away for a new dosing schedule. Depending on your doctors instructions and Side effects: DayQuil can cause side effects such as drowsiness, dizziness, nausea, vomiting, and stomach upset. If you think there has been an overdose, call your poison control center or get medical care right away. Boxed warnings alert doctors and patients about drug effects that may be dangerous. All rights reserved. In clinical trials, serious allergic reactions occurred in 0.1% to 1.5% of people taking Injectafer. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. This treatment course is split into two doses of the drug, which are given at least 7 days apart. other treatments you receive, you will need to go back for several treatments with Venofer. It may also cause nervousness, restlessness, and difficulty sleeping in some people. (And Injectafer is used to treat IDA.) If you have any of these health problems: Too much iron in your body or anemia from a cause other than low iron. Hemoglobin is a protein thats found in your RBCs. Last updated August 20, 2020. TheNational Instituteof Health (NIH) and the U.S. Food andDrug Administration(FDA) monitor theside effectsof new and approved medications to ensure safety. In clinical studies, diarrhea was reported in less than 1% of people taking Injectafer. If you have iron deficiency anemia (IDA), consuming moderate amounts of alcohol may be safe, if your doctor tells you its OK. (With IDA, you have a low level of red blood cells thats caused by not having enough iron.). Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. Your doctor will do laboratory tests to monitor your response. The signs and symptoms of anaphylaxis include dizziness or fainting, skin flushing and itchiness, difficulty breathing, rapid heart rate, low blood pressure and sudden anxiety. The factors influencing how longside effectslast may not provide the answer most are looking for, but it does explain why some people cant take certain medications because theside effectsareunbearable. For more information and to find out if youre eligible for support, call 877-4-IV-IRON (877-448-4766) or visit the program website. But for other people, doing so could lead to having too much iron in their body. Also, keep in mind that if your anemia is causing certain symptoms, treatment with Injectafer may help those symptoms go away. These are not all of the side effects that may occur. They can give you tips on how to deal with any side effects that may be bothersome. Speak to yourhealth careprofessional for medical advice on if the dosage should bereduced. Most of these side effects may go away within a few days or a couple of weeks. With IV infusion, the drug is given as a slow drip into your vein over a period of time. And this over-activation is what may lead to an allergic reaction or a delayed allergic reaction. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. So you wont pick up this medication from a pharmacy. This hormone is made by your kidneys. Innovators Monograph The potential side effects of Daxxify are nearly identical to that of Botox bruising, headaches, and droopy eyelids with one big difference: They could last longer. (For more information on Venofer, see the Injectafer vs. Venofer section above). In the US - Call your doctor for medical advice about side effects. Effectiveness of Injectafer compared with iron thats taken by mouth. If you have questions about side effects, call your doctor. If needed, theyll recommend treatment, including certain medications. If you are allergic to Venofer; any part of this medicine; or any other drugs, foods, or substances. There may be drug take-back programs in your area. Typical Injectafer doses for iron deficiency anemia (IDA) depends on your body weight. If you have questions about using Injectafer for anemia during pregnancy, talk with your doctor. You will be watched closely for at least 30 minutes to make sure you do not have an allergic reaction. Note: The Food and Drug Administration (FDA) tracks side effects of drugs they have approved. The next time the doctor prescribesprescription medication, ask aboutcommonside effectsand if they are known to last a short or longtime. MNT is the registered trade mark of Healthline Media. And if you dont have an allergic reaction to your first dose of a drug, its typically safe to assume you wont have an allergic reaction to doses that follow. Do not exceed 1,500 mg of iron per dosing course. intense abdominal pain. You may also report side effects at https://www.fda.gov/medwatch. Depending on your anemia symptoms, your weight changes may be different than those described here. WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Dizziness. Check with your pharmacist if you have questions about the best way to throw out drugs. But for most people whove developed hypophosphatemia with Injectafer, the condition resolved within 3 months. Below are examples of these side effects. A healthcare provider will give you this injection. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. So the goal of IDA treatment with Injectafer is to bring your hemoglobin level back to a value thats within normal range. And these two doses need to be separated by at least 7 days. Severeside effectscan lead to injury or death -drowsinesscan cause a car accident or injury when operating heavymachinery. It will take about three weeks to feel the effects but your fatigue will disappear and you will feel like a new person. fever. Do not start, stop, or change the dosage of any medicines without your doctor's approval. For people with certain medical implants, such as pacemakers, an MRI may pose an . The actual price youll pay depends on your insurance plan and any copays, your location, and the pharmacy you use. These lists dont include all possible side effects. Here's some detail on certain side effects this drug may cause. If you would like to report to the FDA a side effect youve had with Injectafer, you can do so through MedWatch. Now I've just got mild nausea and have felt faint/dizzy a few times which is rare for me. Heart failure: Could a low sodium diet sometimes do more harm than good? Injectafer helps to treat IDA by providing an iron infusion directly into your body. Be ready to tell or show what was taken, how much, and when it happened. Injectafer can cause mild or serious side effects. Usually, but not always, the bigger a person is the slower it takes for drugs to break down and leave the body. Feraheme is also approved to treat IDA in adults who either didnt have improvement in their IDA or had side effects with iron treatment thats taken by mouth. With IDA, you have low hemoglobin levels. 1 0 obj A lack of iron can lead to iron deficiency anaemia if left untreated. Side effectswill last a very long time if the cause of them is not resolved. Your body then uses the iron from Injectafer to make hemoglobin and new RBCs. Cardiovascular health: Insomnia linked to greater risk of heart attack. To help make sure that you dont miss appointments for your Injectafer doses, try setting an appointment reminder on your phone. For instance, there are some experts who believe there are long-lastingside effectsfromCOVIDthat were not aware of just yet. Do not use Injectafer in people with a history of hypersensitivity reactions to Injectafer or any components of the drug product. You would receive 15 mg of Injectafer per kilogram of body weight for each of your two doses. This site is intended for use only by US patients. The infusion will take between 15-30 minutes if it is given in. Its not known if Injectafer is safe to take during pregnancy. Since side effects are similar between 150 mg and 300 mg, a larger dose may increase severity or frequency of side effects. Can poor sleep impact your weight loss goals? Its not known for sure how often this condition occurred during clinical trials, or if it occurred at all during the trials. One study of just under 5000 HRT users found that 43% were affected. Call your healthcare provider or get medical help right away if you have symptoms of an allergic reaction, including but not limited to rash, chest pain, cough, dizziness, passing out, shortness of breath, sweating or throat tightness. Last updated on Feb 20, 2023. Injectafer should be stored between 68F to 77F (20C to 25C). wAd**CgI%"nn{Oa[q{r5 2 0 obj Your doctor will monitor your hemoglobin level to tell if Injectafer is working for you. Injectafer can be exposed to temperatures between 59F to 86F (15C to 30F) for a short period of time. This gives a total cumulative dose of 1,500 mg of Injectafer. While this may seem like it would be out of a persons body quickly, the rate of it being broken down is much slower afterward. Headache. The drug helps increase your hemoglobin level back to a value thats within the normal range. upper respiratory infection. You may report side effects to FDA at 1-800-FDA-1088. "The most common side effects to COVID vaccines include pain at the injection site, fevers, chills, nausea, headaches, tiredness, and painful or swollen lymph nodes in the arm where the vaccine. Some people are simply allergic to an active ingredient in the medication, so the body responds undesirably. If this happens to you, your doctor may recommend that you receive another treatment course of Injectafer. This information should not be used to decide whether or not to take Venofer or any other medicine. Yes, in some cases it may. Its FDA-approved to treat iron deficiency anemia (IDA) in adults. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. Before taking Injectafer, be sure to tell your doctor or pharmacist about any medications you take, including any over-the-counter vitamins or supplements. Injectafer and Venofer are both brand-name drugs. 5 0 obj Details. <> VenAccess is a trademark of Vifor (International) Inc. Switzerland. If you have questions about the safety of breastfeeding while youre taking Injectafer, talk with your doctor. Upset stomach or throwing up. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. The rest of the people switched from taking iron by mouth to taking an iron product other than Injectafer thats given by IV. And this would give you a total cumulative Injectafer dose of 1,440 mg. Injectafer should be given in two doses. Injectafer infusions are given over a period of at least 15 minutes. The dosing for iron replacement treatment in pediatric patients less than 2 years old with Peritoneal or Hemodialysis-Dependent CKD or Non-Dialysis-Dependent CKD have not been established. Serious side effects, which are explained in more detail below in Side effect details, include: You may wonder how often certain side effects occur with this drug. Most mild side effects of Injectafer typically go away within about 30 minutes of receiving your dose of the drug. Side effects are uncomfortable reactions to medications or drugs. Call your doctor for medical advice about side effects. During Injectafer treatment, your doctor will likely order blood tests. Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat. XAO$$d|0tX1`Q$Il#FBm}{#h!/;[bOvvg7 ?tMl7/+wya^,~PA}6&Ftb19OeJ6-a3acKjcpkeGq+7/nO AJJ:Okyfp;xw|]McmK?9"t0m%. But its important to note that these studies werent designed to show whether Injectafer is safe to use during pregnancy. Its not known whether its safe to breastfeed while youre taking Injectafer. Both Injectafer and Venofer belong to a class of medications called iron replacement products. Maintain a well-balanced diet, and follow any dietary guidelines as directed by your doctor. endobj Limited data indicate that breastmilk iron is not increased after intravenous infusion of Venofer. This is why family members often have the same issues with drugs as others in theirfamily. The way thatprescription drugsand evenover-the-countermedications interact with a body is influenced by manyfactors. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Venofer only for the indication prescribed. If you have more questions about how Injectafer will affect your anemia, talk with your doctor. I used to get a different type but my . This material is provided for educational purposes only and is not intended for medical advice, diagnosis, or treatment.
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